Variables:
A data frame with 236 observations on the following 7 variables.
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treatment
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the treatment group, a factor with levels placebo and Progabide.
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base
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the number of seizures before the trial.
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age
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the age of the patient.
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seizure.rate
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the number of seizures (response variable).
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period
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treatment period, an ordered factor with levels 1 to 4.
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subject
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the patient ID, a factor with levels 1 to 59.
Details
In this clinical trial, 59 patients suffering from epilepsy were randomized to groups receiving either the anti-epileptic drug Progabide or a placebo in addition to standard chemotherapy. The numbers of seizures suffered in each of four, two-week periods were recorded for each patient along with a baseline seizure count for the 8 weeks prior to being randomized to treatment and age. The main question of interest is whether taking progabide reduced the number of epileptic seizures compared with placebo.